영양제 추천에 활용된 데이터 및 참고 출처

[건강기능식품의 기능별 정보 참고]

[건강기능식품의 원료 정보 참고]

[식품 이력 정보 참고]

[엽산]

  • Yadav U, Kumar P, Rai V. Maternal biomarkers for early prediction of the neural tube defects pregnancies. Birth Defects Res. 2021 Apr 15;113(7):589-600. doi: 10.1002/bdr2.1842. Epub 2020 Nov 13. PMID: 33188559.
  • Shere M, Bapat P, Nickel C, Kapur B, Koren G. Association Between Use of Oral Contraceptives and Folate Status: A Systematic Review and Meta-Analysis. J Obstet Gynaecol Can. 2015 May;37(5):430-438. doi: 10.1016/S1701-2163(15)30258-9. PMID: 26168104.

[철분]

  • Dobner J, Kaser S. Body mass index and the risk of infection - from underweight to obesity. Clin Microbiol Infect. 2018 Jan;24(1):24-28. doi: 10.1016/j.cmi.2017.02.013. Epub 2017 Feb 20. PMID: 28232162.
  • Low MS, Speedy J, Styles CE, De-Regil LM, Pasricha SR. Daily iron supplementation for improving anaemia, iron status and health in menstruating women. Cochrane Database Syst Rev. 2016 Apr 18;4(4):CD009747. doi: 10.1002/14651858.CD009747.pub2. PMID: 27087396; PMCID: PMC10182438.

[비타민C]

  • Brubacher D, Moser U, Jordan P. Vitamin C concentrations in plasma as a function of intake: a meta-analysis. Int J Vitam Nutr Res. 2000 Sep;70(5):226-37. doi: 10.1024/0300-9831.70.5.226. PMID: 11068703.
  • Tang Q, Yang H, Liu X, Zou Y, Lv X, Chen K. Efficacy and Safety of Oral Herbal Drugs Used as Adjunctive Therapy for Melasma: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Evid Based Complement Alternat Med. 2021 Dec 6;2021:9628319. doi: 10.1155/2021/9628319. PMID: 34912468; PMCID: PMC8668325.
  • Nosratabadi S, Ashtary-Larky D, Hosseini F, Namkhah Z, Mohammadi S, Salamat S, Nadery M, Yarmand S, Zamani M, Wong A, Asbaghi O. The effects of vitamin C supplementation on glycemic control in patients with type 2 diabetes: A systematic review and meta-analysis. Diabetes Metab Syndr. 2023 Aug;17(8):102824. doi: 10.1016/j.dsx.2023.102824. Epub 2023 Jul 7. PMID: 37523928.

[비타민B]

  • Gomes F, Bergeron G, Bourassa MW, Fischer PR. Thiamine deficiency unrelated to alcohol consumption in high-income countries: a literature review. Ann N Y Acad Sci. 2021 Aug;1498(1):46-56. doi: 10.1111/nyas.14569. Epub 2021 Feb 11. PMID: 33576090; PMCID: PMC8451800.
  • Lee MC, Hsu YJ, Shen SY, Ho CS, Huang CC. A functional evaluation of anti-fatigue and exercise performance improvement following vitamin B complex supplementation in healthy humans, a randomized double-blind trial. Int J Med Sci 2023; 20(10):1272-1281. doi:10.7150/ijms.86738.

[비타민D]

  • Moradi S, Shahdadian F, Mohammadi H, Rouhani MH. A comparison of the effect of supplementation and sunlight exposure on serum vitamin D and parathyroid hormone: A systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2020;60(11):1881-1889. doi: 10.1080/10408398.2019.1611538. Epub 2019 May 20. PMID: 31107101.

[은행잎추출물]

  • Hort J, Duning T, Hoerr R. Ginkgo biloba Extract EGb 761 in the Treatment of Patients with Mild Neurocognitive Impairment: A Systematic Review. Neuropsychiatr Dis Treat. 2023 Mar 23;19:647-660. doi: 10.2147/NDT.S401231. PMID: 36994422; PMCID: PMC10041984.
  • Tan MS, Yu JT, Tan CC, Wang HF, Meng XF, Wang C, Jiang T, Zhu XC, Tan L. Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis. J Alzheimers Dis. 2015;43(2):589-603. doi: 10.3233/JAD-140837. PMID: 25114079.
  • Schneider B. Ginkgo-biloba-Extrakt bei peripheren arteriellen Verschlusskrankheiten. Meta-Analyse von kontrollierten klinischen Studien [Ginkgo biloba extract in peripheral arterial diseases.

[오메가3]

  • Welty FK. Omega-3 fatty acids and cognitive function. Curr Opin Lipidol. 2023 Feb 1;34(1):12-21. doi: 10.1097/MOL.0000000000000862. Epub 2022 Nov 25. PMID: 36637075; PMCID: PMC11878108.
  • Giannaccare G, Pellegrini M, Sebastiani S, Bernabei F, Roda M, Taroni L, Versura P, Campos EC. Efficacy of Omega-3 Fatty Acid Supplementation for Treatment of Dry Eye Disease:
  • Simopoulos AP. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med (Maywood). 2008 Jun;233(6):674-88. doi: 10.3181/0711-MR-311.
  • Wang T, Zhang X, Zhou N, Shen Y, Li B, Chen BE, Li X. Association Between Omega-3 Fatty Acid Intake and Dyslipidemia: A Continuous Dose-Response Meta-Analysis of Randomized Controlled Trials. J Am Heart Assoc. 2023 Jun 6;12(11):e029512. doi: 10.1161/JAHA.123.029512. Epub 2023 Jun 2. PMID: 37264945; PMCID: PMC10381976.
  • Hu J, Liu Z, Zhang H. Omega-3 fatty acid supplementation as an adjunctive therapy in the treatment of chronic kidney disease: a meta-analysis. Clinics (Sao Paulo). 2017 Jan 1;72(1):58-64. doi: 10.6061/clinics/2017(01)10. PMID: 28226034; PMCID: PMC5251198.

[비오틴]

  • Patel DP, Swink SM, Castelo-Soccio L. A Review of the Use of Biotin for Hair Loss. Skin Appendage Disord. 2017 Aug;3(3):166-169. doi: 10.1159/000462981. Epub 2017 Apr 27. PMID: 28879195; PMCID: PMC5582478.

[바나바잎추출물]

  • López-Murillo LD, González-Ortiz M, Martínez-Abundis E, Cortez-Navarrete M, Pérez-Rubio KG. Effect of Banaba (Lagerstroemia speciosa) on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion.

[크롬]

  • Vladeva SV, Terzieva DD, Arabadjiiska DT. Effect of chromium on the insulin resistance in patients with type II diabetes mellitus. Folia Med (Plovdiv). 2005;47(3-4):59-62. PMID: 16761396.

[코엔자임Q10]

  • Borghi C, Cicero AF. Nutraceuticals with a clinically detectable blood pressure-lowering effect: a review of available randomized clinical trials and their meta-analyses. Br J Clin Pharmacol. 2017 Jan;83(1):163-171. doi:
  • Borghi C, Cicero AF. Nutraceuticals with a clinically detectable blood pressure-lowering effect: a review of available randomized clinical trials and their meta-analyses. Br J Clin Pharmacol. 2017 Jan;83(1):163-171. doi: 10.1111/bcp.12902. Epub 2016 Mar 15. PMID: 26852373; PMCID: PMC5338151.

[스페인감초추출물]

  • Wang Q, Yao C, Li Y, Luo L, Xie F, Xiong Q, Feng P. Effect of polyphenol compounds on Helicobacter pylori eradication: a systematic review with meta-analysis. BMJ Open. 2023 Jan 5;13(1):e062932. doi:

[생균제제]

  • Zhang C, Jiang J, Tian F, Zhao J, Zhang H, Zhai Q, Chen W. Meta-analysis of randomized controlled trials of the effects of probiotics on functional constipation in adults. Clin Nutr. 2020 Oct;39(10):2960-2969. doi:

[밀크씨슬]

  • Shahsavari K, Ardekani SS, Ardekani MRS, Esfahani MM, Kazemizadeh H, Jamialahmadi T, Iranshahi M, Khanavi M, Hasanpour M. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury. BMC Complement Med Ther. 2025 Apr 12;25(1):134. doi: 10.1186/s12906-025-04886-y. PMID: 40221681; PMCID: PMC11992775.

[글루타치온]

  • Honda Y, Kessoku T, Sumida Y, Kobayashi T, Kato T, Ogawa Y, Tomeno W, Imajo K, Fujita K, Yoneda M, Kataoka K, Taguri M, Yamanaka T, Seko Y, Tanaka S, Saito S, Ono M, Oeda S, Eguchi Y, Aoi W, Sato K, Itoh Y, Nakajima A. Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. BMC Gastroenterol. 2017 Aug 8;17(1):96. doi: 10.1186/s12876-017-0652-3. PMID: 28789631; PMCID: PMC5549431.
  • Vairetti M, Di Pasqua LG, Cagna M, Richelmi P, Ferrigno A, Berardo C. Changes in Glutathione Content in Liver Diseases: An Update. Antioxidants (Basel). 2021 Feb 28;10(3):364. doi: 10.3390/antiox10030364. PMID:

[감마리놀렌산]

  • Horrobin DF. The role of essential fatty acids and prostaglandins in the premenstrual syndrome. J Reprod Med. 1983 Jul;28(7):465-8. PMID: 6350579.

[질유산균]

  • Zahedifard T, Khadivzadeh T, Rakhshkhorshid M. The Role of Probiotics in the Treatment of Vulvovaginal Candidiasis: A Systematic Review and Meta-Analysis. Ethiop J Health Sci. 2023 Sep;33(5):881-890. doi: 10.4314/ejhs.v33i5.18. PMID: 38784519; PMCID: PMC11111202.

[회화나무열매추출물]

  • Lee J, Kim KW, Kim HK, Chae SW, Jung JC, Kwon SH, Rheu CH. The effect of Rexflavone (Sophorae fructus extract) on menopausal symptoms in postmenopausal women: a randomized double-blind placebo controlled clinical trial. Arch Pharm Res. 2010 Apr;33(4):523-30. doi: 10.1007/s12272-010-0405-0. Epub 2010 Apr 27. PMID: 20422360.
  • Ahn JW, Kim HS, Damodar K, Shin HH, Kim KM, Park JY, Yoo YM, Jung JC, Joo SS. Therapeutic Advantages of Isoflavone Glycoside and Aglycone Forms of Sophoricoside in the Amelioration of Postmenopausal Symptoms: Bone Health, Metabolic Regulation, and Systemic Inflammation. Molecules. 2025 May 20;30(10):2218. doi: 10.3390/molecules30102218. PMID: 40430390; PMCID: PMC12113653.

[쏘팔메토]

  • Wilt TJ, Ishani A, Stark G, MacDonald R, Lau J, Mulrow C. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA. 1998 Nov 11; 280(18):1604-9. doi: 10.1001/jama.280.18.1604. Erratum in: JAMA 1999 Feb 10; 281(6):515. PMID: 9820264.

[엠에스엠]

  • Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ. Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis. Br J Sports Med. 2018 Feb;52(3):167-175. doi: 10.1136/bjsports-2016-097333. Epub 2017 Oct 10. PMID: 29018060.

[마그네슘]

  • Schreiber JU, Lysakowski C, Fuchs-Buder T, Tramèr MR. Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials. Anesthesiology. 2005 Oct;103(4):877-84. doi: 10.1097/00000542-200510000-00027. PMID: 16192781.
  • Effatpanah M, Rezaei M, Effatpanah H, Effatpanah Z, Varkaneh HK, Mousavi SM, Fatahi S, Rinaldi G, Hashemi R. Magnesium status and attention deficit hyperactivity disorder (ADHD): A meta-analysis. Psychiatry Res. 2019 Apr;274:228-234. doi: 10.1016/j.psychres.2019.02.043. Epub 2019 Feb 19. PMID: 30807974.
  • Chiu HY, Yeh TH, Huang YC, Chen PY. Effects of Intravenous and Oral Magnesium on Reducing Migraine: A Meta-analysis of Randomized Controlled Trials. Pain Physician. 2016 Jan;19(1):E97-112. PMID: 26752497.
  • Gorica Djokic, Petar Vojvodić, Davor Korcok, Anita Agic, Anica Rankovic, Vladan Djordjevic, Aleksandra Vojvodic, Tatjana Vlaskovic-Jovicevic, Zorica Peric-Hajzler, Dusica Matovic, Jovana Vojvodic, Goran Sijan, Uwe Wollina, Michael Tirant, Nguyen Van Thuong, Massimo Fioranelli, Torello Lotti. The Effects of Magnesium – Melatonin - Vit B Complex Supplementation in Treatment of Insomnia : 2019 Aug 30;7(18):3101–3105. doi: 10.3889/oamjms.2019.771

[칼마디]

  • Weaver CM, Alexander DD, Boushey CJ, Dawson-Hughes B, Lappe JM, LeBoff MS, Liu S, Looker AC, Wallace TC, Wang DD. Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation. Osteoporos Int. 2016 Jan;27(1):367-76. doi: 10.1007/s00198-015-3386-5. Epub 2015 Oct 28. Erratum in: Osteoporos Int. 2016 Aug;27(8):2643-2646. doi: 10.1007/s00198-016-3699-z. PMID: 26510847; PMCID: PMC4715837.
  • Shi L, Zhu H, Ma J, Shi LL, Gao F, Sun W. Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2021 Feb 5;16(1):111. doi: 10.1186/s13018-021-02264-1. PMID: 33546717; PMCID: PMC7863353.
  • Cranney A, Horsley T, O'Donnell S, Weiler H, Puil L, Ooi D, Atkinson S, Ward L, Moher D, Hanley D, Fang M, Yazdi F, Garritty C, Sampson M, Barrowman N, Tsertsvadze A, Mamaladze V. Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess (Full Rep). 2007 Aug;(158):1-235. PMID: 18088161; PMCID: PMC4781354.

[비타민K2]

  • Ma ML, Ma ZJ, He YL, Sun H, Yang B, Ruan BJ, Zhan WD, Li SX, Dong H, Wang YX. Efficacy of vitamin K2 in the prevention and treatment of postmenopausal osteoporosis: A systematic review and meta-analysis of randomized controlled trials. Front Public Health. 2022 Aug 11;10:979649. doi: 10.3389/fpubh.2022.979649. PMID: 36033779; PMCID: PMC9403798.

[녹차추출물]

  • Hursel R, Viechtbauer W, Dulloo AG, Tremblay A, Tappy L, Rumpler W, Westerterp-Plantenga MS. The effects of catechin rich teas and caffeine on energy expenditure and fat oxidation: a meta-analysis. Obes Rev. 2011 Jul;12(7):e573-81. doi: 10.1111/j.1467-789X.2011.00862.x. Epub 2011 Mar 2. PMID: 21366839.

[아연]

  • Sanna A, Firinu D, Zavattari P, Valera P. Zinc Status and Autoimmunity: A Systematic Review and Meta-Analysis. Nutrients. 2018 Jan 11;10(1):68. doi: 10.3390/nu10010068. PMID: 29324654; PMCID: PMC5793296.

[프로폴리스]

  • Zhong-Yong L, ZHi-Qing D, Li-Qiong X, Poorasadollah E, Shirvani S. The impact of propolis supplementation on inflammatory biomarkers: A meta-analysis and systematic review of randomized controlled clinical trials. Prostaglandins Other Lipid Mediat. 2024 Dec;175:106915. doi: 10.1016/j.prostaglandins.2024.106915. Epub 2024 Oct 28. PMID: 39490733.

[테아닌]

  • Hidese S, Ogawa S, Ota M, Ishida I, Yasukawa Z, Ozeki M, Kunugi H. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients. 2019 Oct 3;11(10):2362. doi: 10.3390/nu11102362. PMID: 31623400; PMCID: PMC6836118.
  • Keiko Unno, Shigenori Noda, Yohei Kawasaki, Hiroshi Yamada, Akio Morita, Kazuaki Iguchi, Yoriyuki Nakamura. Reduced Stress and Improved Sleep Quality Caused by Green Tea Are Associated with a Reduced Caffeine Content : 2017 Jul 19;9(7):777. doi: 10.3390/nu9070777.

[비타민B12]

  • Geng C, Yang Z, Xu P, Zhang H. Vitamin B12 deficiency is associated with narcolepsy. Clin Neurol Neurosurg. 2022 Jan;212:107097. doi: 10.1016/j.clineuro.2021.107097. Epub 2021 Dec 18. PMID: 34942572.

[콜라겐]

  • de Miranda RB, Weimer P, Rossi RC. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. Int J Dermatol. 2021 Dec;60(12):1449-1461. doi: 10.1111/ijd.15518. Epub 2021 Mar 20. PMID: 33742704.

[히알루론산]

  • Gao YR, Wang RP, Zhang L, Fan Y, Luan J, Liu Z, Yuan C. Oral administration of hyaluronic acid to improve skin conditions via a randomized double-blind clinical test. Skin Res Technol. 2023 Nov;29(11):e13531. doi: 10.1111/srt.13531. PMID: 38009035; PMCID: PMC10661223.

[셀레늄]

  • Hasani M, Djalalinia S, Khazdooz M, Asayesh H, Zarei M, Gorabi AM, Ansari H, Qorbani M, Heshmat R. Effect of selenium supplementation on antioxidant markers: a systematic review and meta-analysis of randomized controlled trials. Hormones (Athens). 2019 Dec;18(4):451-462. doi: 10.1007/s42000-019-00143-3. Epub 2019 Dec 10. Erratum in: Hormones (Athens). 2020 Sep;19(3):451. doi: 10.1007/s42000-020-00224-8. PMID: 31820398.

[홍국]

  • Rahmani P, Melekoglu E, Tavakoli S, Malekpour Alamdari N, Rohani P, Sohouli MH. Impact of red yeast rice supplementation on lipid profile: a systematic review and meta-analysis of randomized-controlled trials. Expert Rev Clin Pharmacol. 2023 Jan;16(1):73-81. doi: 10.1080/17512433.2023.2138342. Epub 2022 Oct 25. PMID: 36259545.

[콜레우스 포스콜리]

  • Godard MP, Johnson BA, Richmond SR. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obes Res. 2005 Aug;13(8):1335-43. doi: 10.1038/oby.2005.162. PMID: 16129715.

[칼마디&아연]

  • Dobner J, Kaser S. Body mass index and the risk of infection - from underweight to obesity. Clin Microbiol Infect. 2018 Jan;24(1):24-28. doi: 10.1016/j.cmi.2017.02.013. Epub 2017 Feb 20. PMID: 28232162.